Pterostilbene Benefits And Side Effects
Pterostilbene is derived from a compound called resveratrol. It is somehow more powerful than resveratrol and also it is a better way to get the same effect of resveratrol. A lot of nootropics contain Pterostilbene. It is considered to be the best ingredient for brain supplements. This ingredient does not just improve the brain function but also boosts the cognitive performance. Pterostilbene is popularly used in Europe to help the patients who suffer from cognitive decline. It seemed to work on seizures and stroke. This is why this ingredient is very often included in the use of many brain supplements called nootropics. It can also boost your productivity and mental ability without losing focus on anything throughout your day. Nootropics are energy boosting supplements that come in many different shapes and sizes. They also include blends with Pterostilbene and other natural ingredients that help in enhancing the benefits. It works more efficiently and effectively when combined with blends.
The ingredient is known for benefiting mental health in many ways by improving mental clarity, lowering blood sugar, and adding muscular and cardiovascular health. This dietary compound is commonly found in blueberries. It acts similar to the compounds found in red wine. So it is not the red wine that gives you the cardiovascular benefits but it is the resveratrol, a compound found in red wine that actually gives you the benefits. It provides you with powerful anti-aging effects and antioxidant benefits by contributing to cognitive health. This is done by increasing the blood circulation and ensuring your brain has proper levels of dopamine.
This derivative actively helps in providing the anti-aging qualities. It destroys the free radicals that are responsible for degenerating your cells. It also prevents the release of enzymes that cause your cells to become inflamed. It also helps in avoiding long terms problems caused by disorders and diseases caused by chronic inflammation. One of the best qualities of Pterostilbene is its ability to influence gene expression. It can also moderate the sensitivity of genetic communication. If your DNA is working to program specific cell death while rapidly multiplying the cells that are found in any genetic disorders, then Pterostilbene will focus on preventing these messages being sent from the DNA. Thus it allows you to slow the progression of the genetic diseases by slowing down the cognitive decline.
Pterostilbene as any other natural ingredient does not have any severe side effects. When it is combined with many nootropic ingredients, it works really well with choline supplements like Citicoline and Alpha GPC to provide utmost benefits with absolutely no side effects. This ingredient is found in natural form in blueberries and acts just like the Resveratrol found in red wine. It works extremely well when added to health supplements such as nootropics.
This dimethylated derivative of resveratrol is more potent for some mechanisms. It gets easily absorbed by human body and is referred to as a 'better resveratrol' for a reason. Pterostilbene is a methylated stilbene molecule and its structural similarity is same as resveratrol. The only possible difference that we can see between is that the two methoxy groups on the pterostilbene molecule that replace hydroxy groups on the resveratrol molecule. Most of the actions of the two are comparable. However, pterostilbene appears to be better absorbed following oral ingestion and may be a more potent antioxidant and anticancer molecule.
Low doses of pterostilbene seem to hold a lot of benefits for cognition. It is thought to be one of the bioactive components of blueberries. Higher doses may not have shown any neurological effects. However, it is important to note that higher supplemental dosages of pterostilbene seem to have benefitted in reducing cholesterol and glucose. The reduction in blood glucose and improvement in insulin sensitivity was also reported by a few studies. It is also important to note that it is comparable to metformin as the reference drug.
In contrast, pterostilbene appears to be a relatively lacklustreantiinflammatory agent. It seems more potent than resveratrol for its antioxidative and absorption rates. Since there has not been a highly extensive comparison that has been conducted to prove the potency of this ingredient, it would be inaccurate to declare the statement saying pterostilbene is a 'more potent resveratrol'. So it could be okay to say that it may not apply to everything that resveratrol can do. However, it can be considered as a better ingredient considering the observation and a few basic studies.
Pterostilbene, when taken up to 250mg daily in humans for 6-8 weeks, has failed to cause any biochemical or clinical signs of toxicity. This proves that the side effects are not significantly different than placebo. However, it does worsen cholesterol which may be related to an increase in LDL-C seen with this dose when tested elsewhere in hypercholesterolemic adults.